Will a new tenofovir prodrug for the treatment of HIV reduce the risk of nephrotoxicity?

نویسنده

  • Christina M Wyatt
چکیده

The widely used antiretroviral agent tenofovir disoproxil fumarate has been associated with proximal tubular injury and decreased glomerular filtration rate in HIV-infected individuals. Phase 3 trials of a new prodrug, tenofovir alafenamide, suggest a lower potential for kidney injury.

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عنوان ژورنال:
  • Kidney international

دوره 89 1  شماره 

صفحات  -

تاریخ انتشار 2016